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Drug-Disease Modeling

Drug-Disease Modeling

A combined PK/PD/disease model allows to include disease progression in the prediction of biomarkers and clinical outcomes for patients. This can enable quick go/no-go decisions early in development, as well as predicting likelihood of trial success and trial optimization in the target population.

In addition to what is described under advanced PK/PD modeling, PK/PD/disease modeling includes disease progression in the prediction of biomarkers and clinical outcomes for patients as another component of the model. This will allow for a better understanding of the disease and how to treat it. In addition, it leads to a more accurate quantification and assessment of impact of new therapeutic compounds on the disease as well as improved decisions in drug development through simulations.

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